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Three studies offered fresh evidence that widely used vaccines will continue to protect people against the coronavirus for long periods

Three scientific studies released on Monday offered fresh evidence that widely used vaccines will continue to protect people against the coronavirus for long periods, possibly for years, and can be adapted to fortify the immune system still further if needed.

Most people immunized with the mRNA vaccines may not need boosters, one study found, so long as the virus and its variants do not evolve much beyond their current forms — which is not guaranteed. Mix-and-match vaccination shows promise, a second study found, and booster shots of one widely used vaccine, if they are required, greatly enhance immunity, according to a third report.

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Researchers looking into possible benefits of people receiving two different coronavirus vaccines

The most widely used coronavirus vaccines are designed as two-shot inoculations, and nearly everyone worldwide who has had both doses has received the same vaccine both times.

But that is changing, as more countries are allowing — and even, in some cases, encouraging — mix-and-match inoculation, with people receiving a first shot of one vaccine, and then a second shot of a different one. On Tuesday, Germany’s government revealed that Chancellor Angela Merkel had received two different shots, adding to the growing interest in the practice.

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EU drug regulator encouraged by early data on mixing coronavirus vaccines

The European Medicines Agency Wednesday said there are “good scientific grounds” to suggest that mixing COVID-19 vaccines is safe and effective.

That’s because, currently, all the approved vaccines work in a similar way — by stimulating an immune response to the viral spike protein, the EMA said in an email.

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